If you set the profile option to Random, Random Desktop or Random Mobile, set the screen resolution to profile, and use an interval, the screen resolution will randomly change.

Randomly changing the timezone isn't a good idea if you're IP isn't changing. If you use the IP option for the timezone option, the timezone will be automatically set when the browser starts.

Please read the wiki for the options Chameleon offers. If you have a suggestion, create an issue on the GitHub page.